What is steroid?
The so-called steroid, which is a group of structures similar to steroids, performs many important physiological functions in the body (such as estrogen, androgen, cholesterol, adrenocortical hormone, etc.). If artificial methods are used, many substances similar in structure to these molecules can be produced. When used in large quantities, it has some pharmacological effects, which can be used to treat or control a variety of diseases (muscle weakness is one of them).
Prednisolone (commonly known as American Elixir) is a synthetic steroid that is one of the most commonly used drugs for myasthenia gravis. Although its pharmacological effects can be used to control the disease, it is often too broad and often causes many side effects. Due to many factors such as physical factors, dosage, length of taking, etc., the performance and extent of side effects often vary from person to person. Some people are very slight or not obvious, while others are more significant. Generally speaking, the higher the dose, the longer the side effects of the patients are, the more obvious the side effects are, and the others are more significant. In general, the higher the dose, the longer the side effects of the patient are often. However, for the therapeutic needs of the disease, the physician often uses the lowest effective dose within the range of side effects tolerable. This article hopes to bring more awareness of the drug to patients and their families in the muscle weakness club.
It is common to get a good appetite and gain weight. The face becomes rounder (commonly known as the moon face) and it looks fat. The back of the neck (commonly known as the buffalo back), the body becomes fat (especially the abdomen), the limbs become thinner, mainly due to the fat transfer to the abdomen.
The skin becomes thinner and the underlying blood vessels appear redder due to increased skin transparency. Purple streaks are sometimes seen in the chest, abdomen, and thighs, and it is easy to have a bruising phenomenon, and the wound healing is poor. Sometimes acne will be obvious.
Osteoporosis is more likely to occur due to bone loss, and fractures are more likely to occur when accidentally falls, so calcium intake should be increased. In addition, after long-term use, the femoral head at the top of the thigh bone is more prone to necrosis. If necessary, the artificial joint should be replaced by a knife.
The dose is too high or too long, and some people may have weakness in the buttocks and even the shoulder muscles. Muscle atrophy can be seen when it is severe, and it can usually recover slowly after stopping the drug.
High blood pressure:
A small number of people will have elevated blood pressure after long-term use. Therefore, regular blood pressure can detect this situation early.
Taking steroids can sometimes increase blood sugar. When there are obvious more eating, drinking, and more urine (more than three), you should be careful about the possibility of diabetes. Sometimes blood sugar can be detected early and can be detected early.
Some people will feel emotionally happy after taking the medicine, which may be nothing bad. But if the mood becomes depressed, frustrated, insomnia, restlessness, and even serious mental illness, it is not good. If you have this problem, you can find a psychiatrist to help.
Steroids can suppress the immune system, making the body less resistant to pathogens and more susceptible to infection. Recovery after infection will also drag on for a long time.
A small number of patients have cataracts or glaucoma, but this is not very common. If you have this concern, consider an eye exam by an ophthalmologist.
Some people are more likely to cause digestive ulcers when taking steroids. Adding stomach medicine can improve the symptoms of stomach discomfort. In addition, long-term use of steroid patients, due to the body’s ability to produce adrenal cortex hormones have been reduced due to long-term inhibition, the production itself is extremely insufficient, at this time the most likely to suddenly stop the drug, there will be many uncomfortable symptoms, such as body burnout, joints Soreness….etc. In serious cases, there may even be confusion.
Therefore, when the condition is improved or other problems need to be reduced or discontinued, the doctors will be very careful, patiently and slowly reduce the amount, so that the body can adapt, so as not to have uncomfortable symptoms. These are the side effects that are more likely to occur when using steroids to treat myasthenia gravis. But don’t be scared, because these are usually more likely to occur at high doses and long-term use. Steroids are a very effective drug. As long as you work patiently with your doctors, carefully adjust the dosage and pay attention to the severity of side effects, it is generally not a problem.
Only a very small number of patients have very obvious side effects because of their different constitutions. They have to stop taking drugs and switch to other immunosuppressive drugs. Therefore, the proper use of steroids is of great help to the control of myasthenia gravis.